Acetaminophen has actually been associated with circumstances of acute liver failure, from time to time leading to liver transplant and Loss of life.
Opioid analgesics may well boost the neuromuscular-blocking action of skeletal muscle mass relaxants and create a rise in the diploma of respiratory depression.
The following information and facts must be supplied to clients acquiring PERCOCET tablets by their medical professional, nurse, pharmacist, or caregiver:
Percocet is additionally used to deal with reasonable to intense discomfort, but can be prescribed for conditions connected with fever. It will also be utilized to treat breakthrough ache every time a extensive-performing soreness drug doesn’t present adequate reduction.
The combination of oxycodone and acetaminophen hasn't been evaluated for mutagenicity. Oxycodone alone was negative inside of a bacterial reverse mutation assay (Ames), an in vitro chromosome aberration assay with human lymphocytes with out metabolic activation and an in vivo mouse micronucleus assay.
Don't use with another drug that contains acetaminophen with out asking your doctor or pharmacist to start with. Acetaminophen is in many nonprescription and prescription medications (such as suffering/fever medication or cough-and-cold products).
Drug interactions may improve how your prescription drugs get the job done or raise your risk for critical Negative effects. This doc will not have all feasible drug interactions.
Bodily dependence can come about regardless if you take oxycodone or Percocet as directed. Turning more info out to be bodily depending on a drug is not really similar to get more info owning an habit, but Actual physical dependence generally accompanies addiction.
Many of the circumstances of liver damage are related to using acetaminophen at doses that exceed 4000 milligrams a day and sometimes involve multiple acetaminophen-containing products.
Percocet will not be advised for long-expression use simply because acetaminophen has long been located to cause critical liver injury.
Other adverse reactions attained from postmarketing activities with click here PERCOCET tablets are shown by organ program and in lowering get of severity and/or frequency as follows:
Clients ought to be suggested not to more info adjust the medication dose on their own. Alternatively, they have to consult with with their prescribing physician.
Early signs or symptoms following a probably hepatotoxic overdose may perhaps consist of: nausea, vomiting, diaphoresis, and standard malaise. Scientific and laboratory proof of hepatic toxicity may not be obvious until 48 to 72 hours publish-ingestion.
Discomfort medications operate finest if they are utilized as the primary indications of pain take place. In the event you wait till the percocet pain has worsened, the medication might not perform also.